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Génétique Quantitative et Évolution - Le Moulon

Clémentine VITTE

Clémentine VITTE

Junior Investigator, CNRS

Maize evolutionary genomics and epigenomics

clementine.vitte@inrae.fr

+33 (0)1 69 33 23 57

orcid.org/0000-0001-5908-0955

Publications

  • Génétique Quantitative et Évolution - Le Moulon
  • Université Paris-Saclay, INRAE, CNRS, AgroParisTech
  • Ferme du Moulon
  • F-91190 Gif-sur-Yvette

Position and Education

  • CNRS researcher (CR1) Section 23, GQE-Le Moulon (Gif-sur-Yvette, France), 2013-present
  • CNRS researcher (CR2) Section 23, GQE-Le Moulon (Gif-sur-Yvette, France), 2008-2013
  • Postdoctoral fellow (Urgence FRM fellowship), Institut Jacques Monod (Paris, France), 2007
  • Postdoctoral fellow (Lavoisier Egide fellowship), Bennetzen laboratory (Athens, Georgia, USA), 2005-2006
  • PhD student (MENRT fellowship and teaching associate), ESE laboratory, Orsay (France), 2001-2004

Research interests

My current research interest is to understand the interlink between genome structure and function, and how it is challenged by environmental conditions. I am particularly focusing on how structural genome variation brought by transposable elements and gene duplications shape methylome and transcriptome variation. To investigate these questions, I use maize as a model species, with particular interest for the originality of the European germplasm. I use an integrative approach combining bioinformatics analysis of massive parallel sequencing data and molecular biology. My research takes place within the French investment for the future Amaizing program, in which I lead WP3 (www.amaizing.fr).

My past work has been to investigate how LTR retrotransposons impact plant genome size and structure. I first used rice to study the evolutionary dynamics of LTR retrotransposons at the genus and species level. I then extended this work by comparing the amplification and elimination of LTR retrotransposons in five Angiosperm species with diverse genome size and from diverse phylogenetic clades. I also investigated the dynamics of LTR retrotransposon in onion and garden asparagus.

PhD students and post-doctoral fellows

  • Zeineb Achour (PhD student: 2015-present)
  • Sara Castelletti (Amaizing post-doctoral fellow: 2012-1014)
  • Abdul Rehman-Khan (co-supervised PhD student: 2010-2013)

Current collaborations

  • Internal: Karine Alix, Johann Joets, Maud Tenaillon (DyGAP), Alain Charcosset, Stéphane Nicolas (GQMS)

  • National: Catherine Giauffret (UR AgroImpact, Estrées-Mons); Olivier Turc, Claude Welcker and Francois Tardieu (LEPSE, Montpellier); Peter Rogowsky (RDP, Lyon); Sylvie Coursol (IJPB, Versailles); Jean-Philippe Pichon, Hervé Duborjal and Magalie Leveugle (Biogemma, Clermont-Ferrand); Ludivine Soubigout-Taconnat, Véronique Brunaud, Christine Paysant-Leroux and Marie-Laure Martin-Magniette (ISP2, Gif sur Yvette); Hélène Bergès (CNRGV, Toulouse); Hélène Sellier (IE INRA Estrées-Mons), Carine Palaffre (INRA Saint Martin de Hinx).

  • International: Silvio Salvi (Department of Agricultural Sciences, Bologna University, Italy)

Network animation

  • Member of the scientific council of the RTP “Epigenetics in Ecology and Evolution
  • Member of the scientific council of GDR 2157: “Evolution of Transposable elements: from genomes to populations”

Publications

  • Fagny M., Kuijjer ML., Stam M., Joets J., Turc O., Rozière J., Pateyron S., Venon A., Vitte C. . (2021) Identification of Key Tissue-Specific, Biological Processes by Integrating Enhancer Information in Maize Gene Regulatory Networks. Front. Genet., (11) 606285
  • Mabire C., Duarte J., Darracq A., Pirani A., Rimbert H., Madur D., Combes V., Vitte C. , Praud S., Rivière N., Joets J., Pichon JP., Nicolas SD.. (2019) High throughput genotyping of structural variations in a complex plant genome using an original Affymetrix® axiom® array. BMC Genomics, 1 (20) 848
  • Brandenburg JT., Mary-Huard T., Rigaill G., Hearne SJ., Corti H., Joets J., Vitte C. , Charcosset A., Nicolas SD., Tenaillon MI.. (2017) Independent introductions and admixtures have contributed to adaptation of European maize and its American counterparts. PLOS Genetics, 3 (13) e1006666
  • Vitte C. , Fustier MA., Alix K., Tenaillon MI.. (2014) The bright side of transposons in crop evolution. Briefings in functional genomics, 4 (13) 276-95