Anthony VENON

Biologie Moléculaire

     
  • Population genetics
  • Long reads sequencing
  • Transposable Elements
  • Genotyping
  • Molecular Biology
  • Fruit trees

 INRAE, Ingénieur d'Études

 anthony.venon@inrae.fr —   01.69.15.70.81


 Plateau technique de séquençage longs fragments
 Génétique, Évolution et Écologie de la Morphologie Florale

Implication de Anthony Venon dans axe1 60% axe1 Comprendre et éclairer les mécanismes de l'évolution Axe1 Implication de Anthony Venon dans axe2 40% axe2 Comprendre et prédire les bases génétiques des interactions Axe2 Implication de Anthony Venon dans axe3 0% axe3 Comprendre et mobiliser la diversitée cultivée pour répondre aux attentes des acteurs Axe3
 Publications 

  • Génétique Quantitative et Évolution - Le Moulon
  • Université Paris-Saclay, INRAE, CNRS, AgroParisTech
  • IDEEV
  • 12 route 128
  • 91190 Gif-sur-Yvette
Anthony VENON

Parcours académique

  • 2024-… : Ingénieur d’Études INRAE, GQE - Le Moulon (concours internes)
  • 2022-2024 : Assistant Ingénieur INRAE, GQE - Le Moulon (concours internes)
  • 2018-2020 : Master de Biologie Moléculaire et Cellulaire (Sorbonne Université, Paris)
  • 2014-2022 : Technicien de Recherche, INRAE, GQE - Le Moulon (concours externes)
  • 2014 : Licence professionnelle en Amélioration Génétique des Plantes (Université Paul Sabatier, Toulouse)
  • 2013 : BTS Biotechnologies (Lycée Jacques Monod, Orléans)

Responsabilités

Research interests

In the seq (40%), I am involved in pioneering work with new sequencing technology. I have chosen to utilize Oxford Nanopore Technology (ONT) to enable long-read sequencing (collaboration David Ogereau). My responsibilities encompass managing all long-read sequencing projects across the laboratory, particularly collaborating with the Ge2MorF, GEvAD, BASE, ACEP and GQMS teams. We employ ONT for studying structural variations, transcriptomics (alternative splicing), and epigenomics (5mC marks on DNA) in apples, nigella, yeast and maize to address evolutionary scientific questions. Additionally, I developed ATAC sequencing in maize, collaborating closely with Maud Fagny and Clémentine Vitte from the GEvAD team, to investigate regulated gene expression in complex phenotypes and its role in environmental adaptation.

Within the Ge2MorF team (60%), we employ a diverse array of methodologies, including laboratory experiments, fieldwork, modeling, molecular biology and genomics. In this capacity, I oversee all molecular biology projects within the team, which encompass tasks such as DNA/RNA extraction, Sanger Sequencing, ONT sequencing, EM-sequencing, cloning, and more.

Furthermore, my research focus revolves around transposable elements (TEs) and their impact on the adaptation of apple trees. To achieve this, I have constructed a TE database using Illumina sequencing data from 23 apple trees. Subsequently, I have analyzed NGS data from 280 cultivated and wild Malus genotypes. These findings are expected to shed light on the contribution of transposable elements to the adaptation of Malus domestica, the cultivated apple tree (in collaboration with Karine Alix and Amandine Cornille).

Financements

  • 2024 : Projet Digital PCR. SPS : 20k euros (collaborations Carine Remoué et David Ogereau).
  • 2023 : Projet PIONEERING: PromethION long REad sEquencING (SPS: 12k euros; Biosphera: 10k euros; INRAe (BAP): 5k euros; AgroParisTech: 10k euros). Montant total : 37k euros

Publications

  • Chen X., Avia K., Forler A., Remoué C., Venon A. , Rousselet A., Lucas G., Kwarteng AO., Rover R., Le Guilloux M., Belcram H., Combes V., Corti H., Olverà-Vazquez S., Falque M., Alins G., Kirisits T., Ursu TM., Roman A., Volk GM., Bazot S., Cornille A.. (2023) Ecological and evolutionary drivers of phenotypic and genetic variation in the European crabapple [ Malus sylvestris (L.) Mill.], a wild relative of the cultivated apple. Annals of Botany, 6 (131) 1025-1037
  • Bina H., Yousefzadeh H., Venon A. , Remoué C., Rousselet A., Falque M., Faramarzi S., Chen X., Samanchina J., Gill D., Kabaeva A., Giraud T., Hosseinpour B., Abdollahi H., Gabrielyan I., Nersesyan A., Cornille A.. (2022) Evidence of an additional centre of apple domestication in Iran, with contributions from the Caucasian crab apple Malus orientalis Uglitzk. to the cultivated apple gene pool. Molecular Ecology, 21 (31) 5581-5601
  • Fagny M., Kuijjer ML., Stam M., Joets J., Turc O., Rozière J., Pateyron S., Venon A. , Vitte C.. (2021) Identification of Key Tissue-Specific, Biological Processes by Integrating Enhancer Information in Maize Gene Regulatory Networks. Frontiers in Genetics, (11) 1703
  • Olvera-Vazquez SG., Remoué C., Venon A. , Rousselet A., Grandcolas O., Azrine M., Momont L., Galan M., Benoit L., David GM., Alhmedi A., Beliën T., Alins G., Franck P., Haddioui A., Jacobsen SK., Andreev R., Simon S., Sigsgaard L., Guibert E., Tournant L., Gazel F., Mody K., Khachtib Y., Roman A., Ursu TM., Zakharov IA., Belcram H., Harry M., Roth M., Simon JC., Oram S., Ricard JM., Agnello A., Beers EH., Engelman J., Balti I., Salhi-Hannachi A., Zhang H., Tu H., Mottet C., Barrès B., Degrave A., Razmjou J., Giraud T., Falque M., Dapena E., Miñarro M., Jardillier L., Deschamps P., Jousselin E., Cornille A.. (2021) Large-scale geography survey provides insights into the colonization history of a major aphid pest on its cultivated apple host in Europe, North America and North Africa. Peer Community Journal, (1)
  • Fustier MA., Martínez-Ainsworth NE., Aguirre-Liguori JA., Venon A. , Corti H., Rousselet A., Dumas F., Dittberner H., Camarena MG., Grimanelli D., Ovaskainen O., Falque M., Moreau L., Meaux J., Montes-Hernández S., Eguiarte LE., Vigouroux Y., Manicacci D., Tenaillon MI.. (2019) Common gardens in teosintes reveal the establishment of a syndrome of adaptation to altitude. PLOS Genetics, 12 (15) e1008512