Anthony VENON

Anthony VENON

Biologie Moléculaire

     
  • Population genetics
  • Apple trees
  • Long reads sequencing
  • Transposable Elements
  • Genotyping
  • Molecular Biology, Fruit trees

 INRAE, Assistant Ingénieur

 anthony.venon@inrae.fr —   +33 (0)1.69.15.70.81


 Ecological genomics of multi-species interactions
 Genetics, Epigenetics and Evolution of the Floral Morphogenesis

 Publications 

  • Génétique Quantitative et Évolution - Le Moulon
  • Université Paris-Saclay, INRAE, CNRS, AgroParisTech
  • IDEEV
  • 12 route 128
  • 91190 Gif-sur-Yvette

Position and Education

  • 2022-… : Assistant Engineer INRAE, GQE – Le Moulon
  • 2018-2020: Master degrees on molecular and cellular biology (Sorbonne university, Paris)
  • 2014-2022: Research Technician INRAE, GQE – Le Moulon
  • 2014: Bachelor on Biotechnology and plant genetic improvement (Paul Sabatier University, Toulouse)
  • 2013: Associate Degree on Biotechnology (Jacques Monod High School, Orléans)

Responsibilities

  • 2023-…: Leader of the long fragment sequencing Platform
  • 2020-… Elected member of the Management Council of the INRAE Biologie et Amélioration des Plantes Department
  • 2015-…. Elected member of the Scientific Council of IDEEV
  • 2014-2018: Quality Assurance Manager in Research

Research interests

In the seq plateform (40%), I am involved in pioneering work with new sequencing technology. I have chosen to utilize Oxford Nanopore Technology (ONT) to enable long-read sequencing (collaboration David Ogereau. My responsibilities encompass managing all long-read sequencing projects across the laboratory, particularly collaborating with the ECLECTIC, Ge2MorF, GEvAD, BASE, ACEP, GQMS and SECF teams. We employ ONT for studying structural variations, transcriptomics (alternative splicing), and epigenomics (5mC marks on DNA) in apples, nigella, yeast and maize to address evolutionary scientific questions. Additionally, I developed ATAC-sequencing in maize, collaborating closely with Maud Fagny and Clémentine Vitte from the GEvAD team, to investigate regulated gene expression in complex phenotypes and its role in environmental adaptation.

Within the Eclectic team (60%), we employ a diverse array of methodologies, including laboratory experiments, fieldwork, modeling, molecular biology, population genetics, and genomics. In this capacity, I oversee all molecular biology projects within the team, which encompass tasks such as DNA/RNA extraction, genotyping (in collaboration with Gentyane), Sanger Sequencing, ONT sequencing, EM-sequencing, TA-cloning, and more. Furthermore, my research focus revolves around transposable elements (TEs) and their impact on the adaptation of apple trees. To achieve this, I have constructed a TE database using Illumina sequencing data from 23 apple trees. Subsequently, I have analyzed NGS data from 280 cultivated and wild Malus genotypes. These findings are expected to shed light on the contribution of transposable elements to the adaptation of Malus domestica, the cultivated apple tree (in collaboration with Karine Alix and Amandine Cornille).

Financements

  • 2023 : PIONEERING project: PromethION long REad sEquencING (SPS: 12k euros; Biosphera: 10k euros; INRAe (BAP): 5k euros; AgroParisTech: 10k euros). total : 37k euros

Publications

  • Chen X., Avia K., Forler A., Remoué C., Venon A. , Rousselet A., Lucas G., Kwarteng AO., Rover R., Le Guilloux M., Belcram H., Combes V., Corti H., Olverà-Vazquez S., Falque M., Alins G., Kirisits T., Ursu TM., Roman A., Volk GM., Bazot S., Cornille A.. (2023) Ecological and evolutionary drivers of phenotypic and genetic variation in the European crabapple [ Malus sylvestris (L.) Mill.], a wild relative of the cultivated apple. Annals of Botany, 6 (131) 1025-1037
  • Bina H., Yousefzadeh H., Venon A. , Remoué C., Rousselet A., Falque M., Faramarzi S., Chen X., Samanchina J., Gill D., Kabaeva A., Giraud T., Hosseinpour B., Abdollahi H., Gabrielyan I., Nersesyan A., Cornille A.. (2022) Evidence of an additional centre of apple domestication in Iran, with contributions from the Caucasian crab apple Malus orientalis Uglitzk. to the cultivated apple gene pool. Molecular Ecology, 21 (31) 5581-5601
  • Fagny M., Kuijjer ML., Stam M., Joets J., Turc O., Rozière J., Pateyron S., Venon A. , Vitte C.. (2021) Identification of Key Tissue-Specific, Biological Processes by Integrating Enhancer Information in Maize Gene Regulatory Networks. Frontiers in Genetics, (11) 1703
  • Olvera-Vazquez SG., Remoué C., Venon A. , Rousselet A., Grandcolas O., Azrine M., Momont L., Galan M., Benoit L., David GM., Alhmedi A., Beliën T., Alins G., Franck P., Haddioui A., Jacobsen SK., Andreev R., Simon S., Sigsgaard L., Guibert E., Tournant L., Gazel F., Mody K., Khachtib Y., Roman A., Ursu TM., Zakharov IA., Belcram H., Harry M., Roth M., Simon JC., Oram S., Ricard JM., Agnello A., Beers EH., Engelman J., Balti I., Salhi-Hannachi A., Zhang H., Tu H., Mottet C., Barrès B., Degrave A., Razmjou J., Giraud T., Falque M., Dapena E., Miñarro M., Jardillier L., Deschamps P., Jousselin E., Cornille A.. (2021) Large-scale geography survey provides insights into the colonization history of a major aphid pest on its cultivated apple host in Europe, North America and North Africa. Peer Community Journal, (1)
  • Fustier MA., Martínez-Ainsworth NE., Aguirre-Liguori JA., Venon A. , Corti H., Rousselet A., Dumas F., Dittberner H., Camarena MG., Grimanelli D., Ovaskainen O., Falque M., Moreau L., Meaux J., Montes-Hernández S., Eguiarte LE., Vigouroux Y., Manicacci D., Tenaillon MI.. (2019) Common gardens in teosintes reveal the establishment of a syndrome of adaptation to altitude. PLOS Genetics, 12 (15) e1008512